The therapeutic strategy is somewhat complicated on occasions by the requirement of various medications such as oral antidiabetic agents and insulin, with the goal of preventing acute decompensation and preventing or limiting long term comorbidity, improving quality of life and decreasing mortality rates. In 2012, approximately 350 million people around the world suffered from some type of DM, with an estimated reduction in lifespan between 5 and 10 years. Chronic hyperglycemia in diabetes has been associated in the long term with damage, dysfunction or failure of certain organs, specifically the eyes, kidneys, nerves, heart, and blood vessels. The Creative Commons Public Domain Dedication waiver ( ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.ĭiabetes mellitus (DM) is a group of metabolic diseases characterized by hyperglycemia as a result of defects in the secretion or action of insulin or both. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made.
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